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Finally ready to
lose the weight?
So are we.
Medically-supervised weight management with GLP-1 class medication — prescribed by HPCSA-registered practitioners (doctors and supervised Clinical Associates) and delivered to your door. No gym. No crash diet. No surgery.
Assessment takes 5 minutes · POPIA protected · No commitment required
GLP-1 therapy covered by leading SA health publications
From assessment to results.
Four simple steps.
Complete Your Assessment
Answer 5 minutes of questions about your health, weight history, and goals. Our clinical AI prepares a comprehensive profile for your practitioner.
Consult with an iScript Practitioner
Meet your HPCSA-registered practitioner (a doctor, or a Clinical Associate under live doctor supervision) via video call. They will review your profile, assess your eligibility, and design your personalised treatment plan. GLP-1 initiation prescriptions are issued or countersigned by a Medical Doctor as required by the medication's Schedule 4 classification.
Receive Your Prescription
If appropriate, your practitioner issues a SAHPRA-registered prescription (or, for Clinical Associate consultations, the prescription is countersigned by the supervising doctor). The prescription is sent electronically to a licensed South African pharmacy — or, where appropriate, dispensed directly under the iScript.health Section 22C Dispensing Doctor licence. Nationwide delivery available.
Monthly Monitoring & Support
Your practitioner checks in every month to review your progress, adjust your dosage, and ensure you're on track. No guesswork — just medically-guided results.
Why so many South Africans are choosing iScript's medical weight loss programme
0%
Average body weight lost
0×
More effective than diet alone
0%
Patients kept weight off
0+
iScript consultations done
* Based on published GLP-1 clinical trial data. Individual results vary. Data from NEJM 2021, 2022 and WHO weight management studies.
Your body isn't broken.
Your biology is
working against you.
Research shows that up to 70% of body weight is genetically determined. When you diet and exercise, your body fights back — slowing your metabolism, increasing hunger hormones, and storing more fat. This is called metabolic adaptation, and it's why traditional diets fail 95% of the time.
GLP-1 class medications work with your body's own hormonal system — the same system that regulates appetite, blood sugar, and metabolism. Instead of fighting your biology, you're correcting it.
🔬 Peer-reviewed evidence
GLP-1 medications were originally developed for Type 2 Diabetes, where they showed a dramatic side effect: significant, sustained weight loss. Published in the New England Journal of Medicine, results showed average losses of 15–22% of total body weight — over 6 times more than lifestyle changes alone.
😔
Diet & Exercise Alone
2–3%
average weight lost (and usually regained)
🎯
Medical Programme
15–22%
average body weight lost and sustained
Beyond weight loss — what patients also report:
Want to know what's possible for you?
Drag the slider to enter your current weight and see how much you could lose with a medically-supervised programme. Based on real iScript patient data.
✓ No obligation — just a free estimate
✓ Based on average clinical outcomes
✓ Your practitioner will set personal targets
Your weight loss potential
Drag to enter your current weight in kilograms.
Potential loss
17 kg
Based on 18% average clinical result
Reach 78 kg in approximately 28 weeks
With medically-supervised treatment
Medical care you can trust.
Results you can see.
6× more effective
Than diet and exercise alone — backed by NEJM clinical data.
HPCSA-registered practitioners (doctors and supervised Clinical Associates)
Every prescription issued by a verified, specialist-level GP.
SAHPRA-registered medication
Only legal, properly registered medication — never grey-market.
Start in 48 hours
Assessment today. Doctor consultation within 48 hours. Prescription sent same day.
Beyond weight loss
Improving diabetes, blood pressure, PCOS, cholesterol and joint health.
AI-powered care
iScript's AI prepares a full clinical brief before every consultation.
South Africans who
changed their lives.
"I've tried everything — banting, gym, shakes. Nothing worked like this. My doctor at iScript understood my body in a way no-one ever had. Down 19kg and I feel completely transformed."
Thandi M. · Johannesburg
Lost 19 kg in 5 months
Type 2 Diabetes (in remission)
SAHPRA & HPCSA Compliance Notice
In accordance with South African regulations, iScript does not advertise specific prescription medication names, molecules, or brand names online. All medications prescribed through iScript are SAHPRA-registered, legally dispensed through licensed South African pharmacies, and prescribed only by HPCSA-registered medical practitioners following a formal clinical consultation. This is not a self-service or over-the-counter programme.
Everything you need to know
The only thing standing
between you and your
goal weight is this button.
Join thousands of South Africans who got serious about their health — with qualified HPCSA-registered practitioners, real medication, and real results.
Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Results vary between individuals. GLP-1 class medication is a prescription-only medicine in South Africa and may only be prescribed following a formal clinical consultation with an HPCSA-registered doctor. iScript is not liable for individual outcomes. All treatments are subject to clinical eligibility assessment. If you are experiencing a medical emergency, call 10177 or visit your nearest emergency room.